Prevalence of Dementia Among US Adults With Autism Spectrum Disorder
2025

Dementia Prevalence in US Adults with Autism

Sample size: 114582 publication Evidence: high

Author Information

Author(s): Vivanti Giacomo PhD, Lee Wei-Lin MAS, Ventimiglia Jonas MAS, Tao Sha MPH, Lyall Kristen ScD, Shea Lindsay L. DrPH

Primary Institution: A.J. Drexel Autism Institute, Drexel University

Hypothesis

What is the prevalence of dementia among US adults with autism spectrum disorder?

Conclusion

The study found a significantly higher prevalence of dementia diagnoses among individuals with autism spectrum disorder compared to the general population.

Supporting Evidence

  • 8.03% of the ASD-only group had a dementia diagnosis.
  • 8.88% of the ASD plus ID group had a dementia diagnosis.
  • The odds of dementia diagnosis increased with age.

Takeaway

This study looked at how many people with autism also have dementia, and it found that many more people with autism have dementia than those without it.

Methodology

This retrospective cohort study analyzed linked Medicare and Medicaid data to assess dementia diagnoses in individuals with autism spectrum disorder.

Potential Biases

There may be risks of bias due to reliance on claims data for diagnosis identification.

Limitations

The study lacked a comparison group and clinical assessments for diagnoses, and it focused solely on insurance beneficiaries.

Participant Demographics

{"age":{"40 or older":63194,"30-39":20754,"40-49":9593,"50-59":7209,"60-64":2288,"≥65":3267},"gender":{"male":80104,"female":34578},"race":{"Black":18627,"Hispanic or Latino":8048,"White":80680}}

Digital Object Identifier (DOI)

10.1001/jamanetworkopen.2024.53691

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