LINE FUSION GENES: a database of LINE expression in human genes
2006
LINE FUSION GENES: A Database of LINE Expression in Human Genes
Sample size: 1329
publication
Evidence: moderate
Author Information
Author(s): Kim Dae-Soo, Kim Tae-Hyung, Huh Jae-Won, Kim Il-Chul, Kim Seok-Won, Park Hong-Seog, Kim Heui-Soo
Primary Institution: Pusan National University
Hypothesis
How do LINE elements affect human gene expression?
Conclusion
The study identified 1,329 genes affected by LINE expression, providing insights into their implications for human evolution and disease.
Supporting Evidence
- 79% of human genes contain at least one LINE element.
- 1,329 genes were identified as being affected by LINE expression.
- The database provides information on tissue distribution and chromosomal location of genes.
Takeaway
Scientists created a database to show how certain parts of our genes are influenced by LINE elements, which are a type of genetic material.
Methodology
The study involved searching 28,171 human genes for LINE elements and analyzing their structures and expression patterns.
Limitations
The database may not include all LINE elements or their effects on gene expression.
Digital Object Identifier (DOI)
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