First Isolation of Hepatitis E Virus Genotype 4 in Europe through Swine Surveillance in the Netherlands and Belgium
2011

First Isolation of Hepatitis E Virus Genotype 4 in Europe through Swine Surveillance

Sample size: 216 publication Evidence: moderate

Author Information

Author(s): Hakze-van der Honing Renate W., van Coillie Els, Antonis Adriaan F. G., van der Poel Wim H. M.

Primary Institution: Wageningen University and Research Centre

Hypothesis

What is the prevalence of Hepatitis E virus (HEV) in swine in the Netherlands and Belgium?

Conclusion

The study found the first reported case of Hepatitis E virus genotype 4 in swine in Europe, which may have public health implications.

Supporting Evidence

  • HEV prevalence in Dutch swine was found to be 15%.
  • In Belgium, 7% of the samples tested positive for HEV.
  • The genotype 4 strain was the first ever reported in swine in Europe.

Takeaway

Researchers found a new type of Hepatitis E virus in pigs in Europe, which could make people sick.

Methodology

Fecal samples from swine were collected and tested for HEV using real-time RT-PCR.

Limitations

The study did not explore the natural transmission of the virus to other animals or humans.

Participant Demographics

Fecal samples were collected from fattening pigs aged 5 to 6 months from various farms.

Digital Object Identifier (DOI)

10.1371/journal.pone.0022673

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