Overview of Clinical Trials for Recurrent Spontaneous Abortion
Author Information
Author(s): Zhou Xiaoling, Lai Fan, Chen Wei, Zhou Congrong, Deng Yi, Wang Tao, Xing Shasha, Diao Haoyang, Tang Mi, Guo Wenmei, Luo Erdan
Primary Institution: Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China
Hypothesis
What are the characteristics of clinical trials related to recurrent spontaneous abortion registered on Clinical Trials.gov?
Conclusion
The study found that existing research efforts on recurrent spontaneous abortion are inadequate for developing effective prevention and treatment strategies.
Supporting Evidence
- 138 clinical trials related to recurrent spontaneous abortion were identified.
- 72 trials were classified as intervention trials and 66 as observational trials.
- Approximately half of the studies had an enrollment of 100 participants or fewer.
- Asia hosted the highest number of clinical trials, followed by Europe and Africa.
- 61 trials focused on individuals with unexplained recurrent spontaneous abortion.
Takeaway
This study looked at many trials about women who have repeated miscarriages to see what treatments are being tested. It found that most trials focus on drug treatments but there aren't enough good studies to help these women.
Methodology
A search was conducted on Clinical Trials.gov to identify trials related to recurrent spontaneous abortion, and 138 trials were analyzed.
Potential Biases
Some trials may have omitted important details during registration.
Limitations
The study only included trials registered on ClinicalTrials.gov, potentially missing others registered in different databases.
Participant Demographics
The majority of trials included only female participants, with a focus on those experiencing unexplained recurrent spontaneous abortion.
Digital Object Identifier (DOI)
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