Gut Microbiome and Metabolome Changes in Sapsaree Dogs by Age
Author Information
Author(s): Son Seon-Hui, Kang Min-Geun, Kang Anna, Kang Yonggu, Kim Kimoon, Kwak Min-Jin, Song Minho, Kim Younghoon
Primary Institution: Seoul National University
Hypothesis
This study investigates age-related changes in the gut microbiota and metabolome of Sapsaree dogs through metagenomic and metabolomic analyses.
Conclusion
The study found that age-related shifts in gut microbiota composition and metabolite profiles occur in Sapsaree dogs.
Supporting Evidence
- Illumina and Nanopore sequencing revealed distinct gut microbiota profiles in Sapsaree dogs based on age.
- Beneficial bacterial genera were less prevalent in senior dogs compared to younger groups.
- Metabolomic analysis showed significant differences in metabolite profiles across age groups.
Takeaway
As Sapsaree dogs get older, their gut bacteria and the substances produced by these bacteria change, which can affect their health.
Methodology
Fecal samples from Sapsaree dogs were analyzed using Illumina and Nanopore sequencing to study gut microbiota and metabolome.
Potential Biases
Potential bias in sample selection and environmental factors affecting gut microbiota.
Limitations
The study primarily focused on a single breed and may not be generalizable to other dog breeds.
Participant Demographics
Sapsaree dogs categorized into three age groups: junior (<1 year), adult (4-6 years), and senior (10-12 years).
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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