Transport processes of radiopharmaceuticals and -modulators
2011

Transport Processes of Radiopharmaceuticals and Modulators

publication Evidence: moderate

Author Information

Author(s): Efferth Thomas, Langguth Peter

Primary Institution: Johannes Gutenberg-University, Mainz, Germany

Conclusion

The review discusses various strategies to improve the transport of radiopharmaceuticals, radiosensitizers, and radioprotectors in cancer therapy.

Supporting Evidence

  • Radiotherapy and radiology are essential in cancer care.
  • Drugs can sensitize tumor cells to radiotherapy or protect normal tissues from radiation damage.
  • Transport processes are crucial for the effectiveness of radiopharmaceuticals and modulators.

Takeaway

This study looks at how certain drugs can help cancer treatments work better by improving how they move in the body.

Methodology

The review summarizes recent concepts on the transport of radiopharmaceuticals, radiosensitizers, and radioprotectors in cells and tissues.

Limitations

The review highlights that many transport proteins have been scarcely investigated and their roles in radiotherapy are not fully understood.

Digital Object Identifier (DOI)

10.1186/1748-717X-6-59

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