Use of Antenatal Corticosteroids Before Preterm Birth in Southeast Asia
Author Information
Author(s): Pattanittum Porjai, Ewens Melissa R, Laopaiboon Malinee, Lumbiganon Pisake, McDonald Steven J, Crowther Caroline A, The SEA-ORCHID Study Group
Primary Institution: Khon Kaen University
Hypothesis
The audit aimed to assess the use of antenatal corticosteroids prior to preterm birth in Southeast Asia.
Conclusion
The use of antenatal corticosteroids prior to preterm birth varied significantly between countries and hospitals, highlighting the need for improved implementation of this effective intervention.
Supporting Evidence
- Antenatal corticosteroids were given to 40% of women who gave birth before 34 weeks.
- Usage varied from 9% to 73% across different countries.
- Infants exposed to corticosteroids had lower stillbirth rates compared to those not exposed.
- Women receiving corticosteroids were less likely to have had previous pregnancies.
Takeaway
Doctors in Southeast Asia sometimes give a medicine to pregnant women at risk of early delivery to help their babies' lungs, but not all hospitals do this enough.
Methodology
Medical records of 9550 women admitted to labor wards were reviewed to assess corticosteroid use and outcomes.
Potential Biases
Potential selection bias due to non-randomized groups.
Limitations
The study was an audit and not a randomized controlled trial, which may introduce selection bias.
Participant Demographics
Women who gave birth at less than 34 weeks gestation, primarily attending public hospitals.
Statistical Information
P-Value
0.01
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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