Nociception Level Monitor and Pain Management in Breast Surgery
Author Information
Author(s): Malachauskiene Laima, Bhavsar Rajesh, Bakke Skule, Keller Jeppe, Bhavsar Swati, Luy Anne-Marie, Strøm Thomas
Primary Institution: Department of Anesthesia and Critical Care Medicine, South Jutland Hospitals, South Denmark University
Hypothesis
Does NOL-guided analgesic delivery reduce opioid consumption and improve perioperative outcomes in breast surgeries?
Conclusion
Using a NOL monitor reduces the amount of opioids needed during breast surgeries without affecting recovery outcomes.
Supporting Evidence
- The study group used significantly less remifentanil (0.9 mg) compared to the control group (1.35 mg).
- The study group also required less morphine (2.5 mg) than the control group (5 mg).
- There was no significant difference in postoperative nausea and vomiting between the groups.
- Both groups had similar eligibility times for discharge from the recovery room.
Takeaway
Doctors used a special monitor to help give less pain medicine during breast surgery, which worked well without causing other problems.
Methodology
This was a randomized controlled trial with 60 female patients undergoing breast cancer surgery, comparing NOL-guided analgesia to standard care.
Limitations
The study may be underpowered to detect differences in postoperative nausea and vomiting due to the small sample size.
Participant Demographics
Female patients aged 18 to 80 years with ASA classification I–IV scheduled for elective mastectomy.
Statistical Information
P-Value
{"remifentanil":0.033,"morphine":0.013,"TCI_remifentanil":0.001}
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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