New Foci of Buruli Ulcer, Angola and Democratic Republic of Congo
2008

New Cases of Buruli Ulcer in Angola and DRC

Sample size: 3 publication Evidence: moderate

Author Information

Author(s): Kibadi Kapay, Panda Mbutu, Tamfum Jean-Jacques Muyembe, Fraga Alexandra G., Filho Adhemar Longatto, Anyo Gladys, Pedrosa Jorge, Nakazawa Yoshinori, Suykerbuyk Patrick, Meyers Wayne M., Portaels Françoise

Primary Institution: Institute of Tropical Medicine, Antwerp, Belgium

Hypothesis

Is artisanal alluvial mining a risk factor for Buruli ulcer?

Conclusion

The study found that three patients with Buruli ulcer were likely infected while engaging in alluvial mining activities along the Kwango/Cuango River.

Supporting Evidence

  • Buruli ulcer is caused by Mycobacterium ulcerans and is prevalent in Africa.
  • The patients had large ulcers and were treated with rifampin and streptomycin.
  • No relapses were observed after follow-up periods of 42, 30, and 28 months.

Takeaway

Three people got a skin disease called Buruli ulcer after working in diamond mines near a river. They got better after treatment.

Methodology

The study involved three patients with laboratory-confirmed Buruli ulcer, treated according to WHO recommendations.

Limitations

The frequency of Buruli ulcer in Angola is not well documented, and further surveys are needed.

Participant Demographics

All patients were residents of Kinshasa, DRC, with ages 13, 28, and 30 years.

Digital Object Identifier (DOI)

10.3201/eid1411.071649

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