Subcapsular Orchiectomy for Advanced Prostate Cancer
Author Information
Author(s): Oleg Rud, Julia Peter, Reza Kheyri, Christian Gilfrich, Ali M. Ahmed, Wieland Boeckmann, Paul G. Fabricius, Matthias May
Primary Institution: St. Elisabeth Klinikum Straubing
Hypothesis
Is subcapsular bilateral orchiectomy an effective primary therapy for patients with bone metastasis in advanced prostate cancer?
Conclusion
Bilateral subcapsular orchiectomy is an effective and advisable first-line therapy for metastasized prostate cancer with low morbidity and no psychological implications.
Supporting Evidence
- The median follow-up was 35 months.
- Median time of tumor remission was 29 months.
- Overall survival time was 36 months.
- 14% of patients experienced minor postoperative complications.
- No psychological problems were reported following the procedure.
Takeaway
Doctors can remove part of the testicles to help treat prostate cancer, and it works well without causing many problems for the patients.
Methodology
This was a single-center retrospective study evaluating 83 patients treated with subcapsular bilateral orchiectomy for bone metastasized prostate cancer.
Potential Biases
The evaluation of psychological disorders was not based on standardized questionnaires, which may introduce bias.
Limitations
The study is retrospective, includes a limited number of patients, and lacks standardized assessment for psychological disorders.
Participant Demographics
Patients had a mean age of 72.1 years, with 63% presenting multiple metastases.
Digital Object Identifier (DOI)
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