Appropriateness of carotid plaque and intima-media thickness assessment in routine clinical practice
2008

Carotid Plaque and Intima-Media Thickness in Clinical Practice

Sample size: 555 publication Evidence: moderate

Author Information

Author(s): Baroncini Liz Andréa Villela, de Oliveira Aguinaldo, Vidal Enrique Antonio, França Graciliano José, Stahlke Paulo Sérgio Dalla Bona, Alessi Alexandre, Précoma Dalton Bertolim

Primary Institution: Center of Health and Biological Sciences-Pontifical Catholic University of Paraná, Paraná, Brazil

Hypothesis

To evaluate the appropriateness of carotid artery studies including IMT measurement and atherosclerotic plaque presence in relation to cardiovascular risk factors.

Conclusion

The study found that carotid artery assessments identified a higher incidence of plaque in patients with CAD, diabetes, and hypertension, with increased IMT in older patients and males.

Supporting Evidence

  • 120 patients (21.62%) presented carotid plaque.
  • 65% of the studies were deemed appropriate.
  • IMT was higher in males and hypertensive patients.
  • There was a linear increase in mean IMT with age.

Takeaway

Doctors checked the neck arteries of 555 patients to see if they had any plaque or thickening, which can be signs of heart problems. They found that older men and those with certain health issues had more plaque.

Methodology

The study involved 555 patients who underwent carotid artery ultrasound to measure IMT and assess plaque presence, with data collected on demographics and cardiovascular risk factors.

Potential Biases

Potential bias in patient selection as many were referred for non-specific symptoms.

Limitations

The study included patients referred for various reasons, including those without cardiovascular risk, which may affect the generalizability of the findings.

Participant Demographics

The sample included 555 patients, with 220 men and a mean age of 67.06 years.

Statistical Information

P-Value

p = 0.0002 for CAD, p = 0.024 for diabetes, p = 0.036 for hypertension

Confidence Interval

95% CI for IMT measurements

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-7120-6-52

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