Urinary Concentrations of Triclosan in the U.S. Population: 2003–2004
2008

Triclosan Levels in U.S. Urine Samples

Sample size: 2517 publication 10 minutes Evidence: moderate

Author Information

Author(s): Antonia M. Calafat, Xiaoyun Ye, Lee-Yang Wong, John A. Reidy, Larry L. Needham

Primary Institution: Centers for Disease Control and Prevention

Hypothesis

This study was designed to assess exposure to triclosan in a representative sample of the U.S. general population.

Conclusion

Triclosan was detected in about three-quarters of urine samples, with concentrations varying by age and income level.

Supporting Evidence

  • 74.6% of urine samples contained triclosan.
  • Concentrations ranged from 2.4 to 3,790 μg/L.
  • Triclosan levels were higher in individuals with higher household incomes.
  • Concentrations peaked in the third decade of life.
  • Detection rates varied by income group.

Takeaway

The study found that many people in the U.S. have triclosan in their urine, especially younger adults and those with higher incomes.

Methodology

Analyzed urine samples using automated solid-phase extraction and mass spectrometry.

Potential Biases

Potential bias due to self-reported income and race/ethnicity data.

Limitations

The study did not include participants under 6 years of age and may not represent all demographics.

Participant Demographics

Participants were from the U.S. general population, aged 6 years and older.

Statistical Information

P-Value

p<0.01

Confidence Interval

95% CI for LSGM concentrations varied by income group.

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1289/ehp.10768

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