Can We Do Away With PTBD?
Author Information
Author(s): R. D. Bapat, N. N. Rege, R. S. Koti, N. K. Desai, S. A. Dahanukar
Primary Institution: Seth G. S. Medical College and K. E. M. Hospital
Hypothesis
Can we do away with Percutaneous Transhepatic Biliary Drainage (PTBD) in patients with surgical jaundice?
Conclusion
The study suggests that PTBD does not improve liver function and may increase mortality due to sepsis.
Supporting Evidence
- Mortality was 57.14% in patients who underwent surgery without PTBD.
- Patients who received Tinospora cordifolia showed improved immune function.
- PTBD did not improve metabolic capacity of the liver.
- Patients treated with Tinospora cordifolia alone had the lowest mortality rate.
Takeaway
Doctors wanted to see if they could skip a procedure called PTBD for patients with jaundice, and they found that not doing it might actually be safer.
Methodology
A prospective study was conducted with 57 patients divided into four groups to compare outcomes with and without PTBD and with or without treatment using Tinospora cordifolia.
Potential Biases
Potential bias due to the exclusion of patients with severe conditions and reliance on subjective measures of improvement.
Limitations
The study excluded patients with disseminated malignancy, hepatocellular carcinoma, and other complications, which may limit the generalizability of the findings.
Participant Demographics
37 men and 20 women, median age 48.5 years, with a weight median of 42.5 kg.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
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