Conjugated linoleic acid content of human plasma
2008

Study on Conjugated Linoleic Acid in Human Plasma

Sample size: 101 publication Evidence: moderate

Author Information

Author(s): Zlatanos Spiros N, Laskaridis Kostas, Sagredos Angelos

Primary Institution: Laboratory of Organic Chemistry, Chemical Engineering Dept., Aristotle University of Thessaloniki

Hypothesis

What is the normal content of conjugated linoleic acid (CLA) in human plasma among different dietary groups?

Conclusion

The study suggests that the lower limit of plasma CLA content is approximately 0.1% of total fatty acids.

Supporting Evidence

  • Group 3, which consumed CLA supplements, had the highest average plasma content of rumenic acid at 0.20%.
  • Group 1, which did not consume dairy, had an average rumenic acid content of 0.08%.
  • Group 2, which consumed normal amounts of dairy, had an average rumenic acid content of 0.14%.

Takeaway

This study looked at how much CLA is in people's blood based on their diet, finding that those who take CLA supplements have more in their blood than those who don't eat dairy.

Methodology

Participants were divided into three groups based on dairy consumption, and blood samples were analyzed for CLA content using gas chromatography.

Limitations

The study's sample size is relatively small, particularly for the group consuming CLA supplements.

Participant Demographics

Participants included 101 German volunteers aged 18 to 65, with equal representation of men and women across the groups.

Digital Object Identifier (DOI)

10.1186/1476-511X-7-34

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