ABDOMINAL MYOSTEATOSIS AND COGNITIVE FUNCTION: INSIGHTS FROM CARDIA STUDY
2024

Abdominal Myosteatosis and Cognitive Function

Sample size: 2501 publication Evidence: moderate

Author Information

Author(s): Acevedo-Fontanez Adrianna, Rosano Caterina, Yaffe Kristine, Carr J Jeffrey, Terry James Greg, Nair Sangeeta, Cvejkus Ryan, Miljkovic Iva

Primary Institution: University of Pittsburgh

Hypothesis

Does abdominal myosteatosis predict cognitive decline in different racial populations?

Conclusion

Abdominal myosteatosis may be a novel risk factor for cognitive decline, particularly in White individuals.

Supporting Evidence

  • Higher IMAT predicted a significant decline in DSST score in Whites.
  • No significant decline in DSST score was observed in Blacks.
  • The study included a diverse sample of men and women.

Takeaway

Having too much fat in your belly can make it harder to think as you get older, especially for White people.

Methodology

The study analyzed the association between abdominal myosteatosis and cognitive decline over five years in a diverse group of men and women.

Potential Biases

Potential bias due to the predominance of cross-sectional studies in the existing literature.

Limitations

The study primarily focused on White and Black populations, which may limit the generalizability of the findings.

Participant Demographics

2501 participants, including 42% Black and 49% women.

Statistical Information

P-Value

<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0794

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