Risk factors for breast cancer in nulliparous women
1999

Risk Factors for Breast Cancer in Women Without Children

Sample size: 2043 publication Evidence: moderate

Author Information

Author(s): Fioretti F, Tavani A, Bosetti C, Vecchia C La, Negri E, Barbone F, Talamini R, Franceschi S

Primary Institution: Istituto di Ricerche Farmacologiche ‘Mario Negri’

Hypothesis

What are the hormonal and lifestyle factors that affect breast cancer risk in nulliparous women?

Conclusion

The study found that many risk factors for breast cancer in nulliparous women are similar to those in the general female population.

Supporting Evidence

  • Breast cancer risk increased with age at menopause.
  • Oral contraceptives and hormone replacement therapy were moderately related to breast cancer risk.
  • Physical activity levels were inversely related to breast cancer risk.

Takeaway

This study looked at women who have never had children and found that things like when they started their periods and their family history can affect their chances of getting breast cancer.

Methodology

Data from two case-control studies conducted in Italy between 1983 and 1994 were analyzed.

Participant Demographics

The study included 1041 nulliparae with breast cancer and 1002 nulliparous controls.

Statistical Information

Confidence Interval

95% CI

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690306

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