Physical Performance and Activity in Older Prostate Cancer Survivors in Comparison with Population-based Matched Controls
2024

Physical Performance in Older Prostate Cancer Survivors

Sample size: 109 publication 10 minutes Evidence: moderate

Author Information

Author(s): Sletten Reidun, Slaaen Marit, Oldervoll Line Merethe, Kjesbu Skjellegrind Håvard, Šaltytė Benth Jūratė, Åstrøm Lennart, Kirkevold Øyvind, Bergh Sverre, Grønberg Bjørn Henning, Rostoft Siri, Bye Asta, Mork Paul Jarle, Berger Christiansen Ola

Primary Institution: Norwegian University of Science and Technology (NTNU)

Hypothesis

Does radical prostate cancer treatment affect long-term physical performance and activity in older men?

Conclusion

Older men's physical performance and activity levels after prostate cancer treatment are similar to those of matched controls, indicating little impact from the treatment.

Supporting Evidence

  • Physical performance scores were comparable between survivors and controls.
  • Survivors had slightly poorer grip strength and one-legged balance.
  • The study included a matched control group from the Trøndelag Health Study.

Takeaway

This study found that older men who had treatment for prostate cancer are just as active and fit as other older men, even years after their treatment.

Methodology

A cross-sectional study comparing physical performance and activity levels between 109 older prostate cancer survivors and 327 matched controls using various physical tests.

Potential Biases

Potential selection bias as responders may represent a fitter subset of the population.

Limitations

The study's small sample size and single-centre design may limit generalizability, and the cross-sectional nature does not allow for causal conclusions.

Participant Demographics

Men aged ≥70 years, with a mean age of 78.3 years for survivors and 78.2 years for controls.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI –7.46; –4.17

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1016/j.euros.2024.11.005

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