Renal function at the time of a myocardial infarction maintains prognostic value for more than 10 years

2011

Renal Function and Long-Term Prognosis After Myocardial Infarction

Sample size: 6653 publication 10 minutes Evidence: high

Author Information

Author(s): Kümler Thomas, Gislason Gunnar H, Kober Lars, Gustafsson Finn, Schou Morten, Torp-Pedersen Christian

Primary Institution: Rigshospitalet, Copenhagen University Hospital, Denmark

Is renal function at the time of a myocardial infarction a long-term prognostic factor?

Renal function is a strong and independent long-term prognostic factor for 10-12 years following a myocardial infarction.

42% of patients had an eGFR below 60 ml/min, indicating chronic renal disease.
The hazard ratio for the lowest eGFR group was 1.72, indicating a significant increase in mortality risk.
Renal function was a significant prognostic factor for up to 16 years after myocardial infarction.

If your kidneys aren't working well when you have a heart attack, it can be a sign that you might have problems for many years after.

The study followed 6653 myocardial infarction patients using survival analysis and Cox proportional hazard models to assess mortality.

Potential bias due to the exclusion of patients with missing renal function data.

The study does not evaluate the effect of duration or changes in renal dysfunction and lacks information on nonfatal outcomes.

Patients were primarily Caucasian, with a significant proportion being older and having comorbidities.

p<0.0001

1.56-1.91

p<0.05

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