Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition
2006

Behavioural Pharmacology and Glutamate Receptors

publication Evidence: high

Author Information

Author(s): Trevor W. Robbins, Emily R. Murphy

Primary Institution: University of Cambridge

Hypothesis

How do glutamate receptors influence learning and memory processes?

Conclusion

The study highlights the critical role of glutamate receptors in various forms of learning and memory.

Supporting Evidence

  • Glutamate receptors are essential for various types of memory, including spatial and recognition memory.
  • Blockade of NMDA receptors impairs learning in specific tasks, indicating their role in memory processes.
  • Research shows that different types of memory are supported by different neural systems.

Takeaway

This study shows that certain brain receptors help us learn and remember things, like how to find our way or recognize objects.

Methodology

The article reviews historical and recent advances in behavioural pharmacology, focusing on glutamate receptors and their role in learning and memory.

Digital Object Identifier (DOI)

10.1016/j.tips.2006.01.009

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