BOV – a web-based BLAST output visualization tool
Author Information
Author(s): Gollapudi Rajesh, Revanna Kashi Vishwanath, Hemmerich Chris, Schaack Sarah, Dong Qunfeng
Primary Institution: Center for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA
Hypothesis
We have developed a web-based program, BLAST Output Visualization Tool (BOV), that allows users to interactively visualize the matching regions of query and database hit sequences.
Conclusion
BOV provides a user-friendly web interface to visualize the standard BLAST output for investigating wide-ranging genomic problems.
Supporting Evidence
- BOV allows users to upload standard BLAST output in pair-wise alignment format.
- The program extracts alignment coordinates to plot matching regions as colored lines or trapezoids.
- Tutorials are provided to guide users through the functional features of BOV.
- BOV can handle both single and batch query datasets.
Takeaway
BOV is a tool that helps scientists see and understand the results from a program that compares DNA sequences, making it easier to find important patterns.
Methodology
The BOV program takes a plain-text BLAST output file and extracts alignment coordinates to generate interactive maps displaying matching regions.
Limitations
The BOV program is not sophisticated in its computer science algorithms and may not handle all types of pair-wise alignment outputs.
Digital Object Identifier (DOI)
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