Infiltrating myoepithelial carcinoma of the breast, a case report and cytologic-histologic correlation
2008

Infiltrating Myoepithelial Carcinoma of the Breast: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Daniel Lingamfelter, Yayan Chen, Kiyoe Kure, Kamani Lankachandra

Primary Institution: Department of Pathology, University of Missouri-Kansas City School of Medicine and Truman Medical Centers

Hypothesis

What role does cytology play in diagnosing myoepithelial carcinoma of the breast?

Conclusion

Fine needle aspiration can establish malignancy in myoepithelial carcinoma, but a specific diagnosis may be challenging due to similarities with other lesions.

Supporting Evidence

  • The cytologic features correlated well with histologic findings.
  • The patient had a 7-cm mass in her left breast.
  • Immunohistochemical markers confirmed the diagnosis of myoepithelial carcinoma.
  • The patient experienced pulmonary metastasis several months later.

Takeaway

This study is about a woman with a rare type of breast cancer, and it shows that doctors can tell if it's cancer using a needle to take a sample, but figuring out exactly what type of cancer it is can be hard.

Methodology

The study involved fine needle aspiration, core needle biopsies, and a simple mastectomy with sentinel node biopsy.

Limitations

The study is based on a single case, which may not represent all instances of myoepithelial carcinoma.

Participant Demographics

52-year-old white female

Digital Object Identifier (DOI)

10.1186/1746-1596-3-7

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