Pregnancy in Inflammatory Bowel Disease: Data from a Real-World Cohort in Germany
Author Information
Author(s): Ayoub Mousa, Muzalyova Anna, Ebigbo Alanna, Nagl Sandra, Römmele Christoph, Classen Johanna, Wanzl Julia, Fleischmann Carola, Ayoub Sami, Tadic Vidan, Schlottmann Jakob, Schnoy Elisabeth
Primary Institution: University Hospital Augsburg
Hypothesis
The study aims to assess the complications occurring during pregnancy in patients with inflammatory bowel disease (IBD) and evaluate the standard of care provided.
Conclusion
Patients with IBD in remission did not present an increased risk of pregnancy complications, while those with active disease faced higher risks of gestational diabetes and fever.
Supporting Evidence
- 85% of women were in remission for at least three months before pregnancy.
- Patients with IBD in remission did not experience a higher risk of pregnancy complications.
- Gestational diabetes occurred in 10% of patients in remission compared to 25% with active disease.
Takeaway
Women with inflammatory bowel disease can have healthy pregnancies if their disease is under control before getting pregnant.
Methodology
The study included a mixed-method approach with retrospective data analysis and a prospective cohort survey of IBD patients who had children.
Limitations
Not all study participants fully completed the questionnaire, and some data were missing due to patients discontinuing treatment.
Participant Demographics
{"total_patients":134,"female_patients":80,"male_patients":54,"median_age":46.5,"age_range":"27-85","diagnosis_distribution":{"Crohn's_disease":69,"ulcerative_colitis":59,"unclassified_IBD":6}}
Digital Object Identifier (DOI)
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