Nanocarriers for Nitric Oxide Delivery

publication Evidence: moderate

Author Information

Author(s): Juliana Saraiva, Samantha S. Marotta-Oliveira, Simone Aparecida Cicillini, Josimar de Oliveira Eloy, Juliana Maldonado Marchetti

Primary Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo

The study investigates the potential of nanocarriers to improve the delivery and therapeutic use of nitric oxide (NO).

Nanocarriers can enhance the stability and delivery of nitric oxide, addressing its limitations in therapeutic applications.

Nanocarriers can load high amounts of nitric oxide and are stable.
Nanotechnology can improve drug delivery systems and reduce side effects.
NO donors can be incorporated into biopolymers for targeted delivery.
Polymeric nanoparticles and micelles have been extensively studied for drug delivery.
Gold nanoparticles can be functionalized for targeted delivery of nitric oxide.

This study shows that tiny carriers can help deliver a gas called nitric oxide better, making it safer and more useful for medicine.

The study reviews various types of nanocarriers and their applications in delivering nitric oxide for therapeutic purposes.

The study notes that while many new NO-releasing molecules exist, few are effective drugs.

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