Association between Manganese Exposure through Drinking Water and Infant Mortality in Bangladesh
2007

Manganese in Drinking Water and Infant Mortality in Bangladesh

Sample size: 3824 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hafeman Danella, Factor-Litvak Pam, Cheng Zhongqi, van Geen Alexander, Ahsan Habibul

Primary Institution: Mailman School of Public Health, Columbia University

Hypothesis

Is there an association between manganese exposure through drinking water and infant mortality in Bangladesh?

Conclusion

The study suggests a possible link between manganese exposure in drinking water and increased infant mortality.

Supporting Evidence

  • Infants exposed to manganese levels above the WHO standard had a higher risk of mortality.
  • The odds ratio for mortality in infants exposed to high manganese was 1.8.
  • Adjustment for other variables did not significantly change the association.
  • Recent marriages showed a stronger association between manganese exposure and infant mortality.

Takeaway

Drinking water with too much manganese might make babies more likely to die before their first birthday.

Methodology

The study analyzed data from a cohort of mothers and infants, assessing water manganese levels and infant mortality rates.

Potential Biases

Potential bias due to reliance on maternal recall for reproductive history and well use.

Limitations

The study relied on retrospective data collection, which may introduce misclassification of exposure and outcome.

Participant Demographics

Participants were mothers from the Health Effects of Arsenic Longitudinal Study cohort in Araihazar, Bangladesh.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95% CI, 1.2–2.6

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.10051

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