Emerging Sensing Technologies for Liquid Biopsy Applications: Steps Closer to Personalized Medicine
2024

Emerging Sensing Technologies for Liquid Biopsy Applications

publication Evidence: high

Author Information

Author(s): Kalligosfyri Panagiota M., Lamprou Eleni, Kalogianni Despina P.

Primary Institution: Department of Chemistry, University of Patras, Greece

Hypothesis

Liquid biopsy techniques can provide early cancer diagnosis and prognosis through the detection of tumor biomarkers in body fluids.

Conclusion

The review highlights recent advancements in biosensing technology for liquid biopsy applications, emphasizing the potential for point-of-care testing.

Supporting Evidence

  • Liquid biopsy is less invasive than tissue biopsy and provides real-time monitoring of cancer.
  • Numerous biosensors have been developed to detect various cancer biomarkers with high specificity.
  • Emerging technologies in biosensing are paving the way for personalized medicine.

Takeaway

Liquid biopsy is like a simple blood test that helps doctors find cancer early by looking for tiny bits of tumor in your blood.

Methodology

The review discusses various biosensing technologies, including colorimetric, fluorescent, electrochemical, SPR, and SERS sensors, for detecting cancer biomarkers.

Limitations

Challenges include low biomarker abundance, high levels of interfering substances, and the need for sensitive detection methods.

Digital Object Identifier (DOI)

10.3390/s24247902

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