Safety of liver resection and effect on quality of life in patients with benign hepatic disease: Single center experience
2011

Safety of Liver Surgery for Benign Tumors and Its Impact on Quality of Life

Sample size: 146 publication Evidence: moderate

Author Information

Author(s): Kamphues Carsten, Engel Sabine, Denecke Timm, Bova Roberta, Hippler-Benscheidt Michael, Puhl Gero, Neuhaus Peter, Seehofer Daniel

Primary Institution: Universitätsklinikum Charité, Campus Virchow Klinikum, Humboldt-Universität, Berlin, Germany

Hypothesis

The study aims to prove the safety of liver resection in treating benign liver tumors and evaluate its effect on patients' quality of life.

Conclusion

Liver resection for benign liver disease is a safe procedure and leads to a significant improvement in quality of life for selected patients.

Supporting Evidence

  • The rate of serious complications was only 4.1% with no postoperative deaths.
  • Quality of life improved significantly after surgery, with a global health status increase from 0.56 to 0.7.
  • Patients reported a significant reduction in symptoms such as pain and fatigue after surgery.

Takeaway

This study shows that removing benign liver tumors is safe and helps people feel better in their daily lives.

Methodology

The study included 146 patients who underwent liver resection for benign tumors, assessing postoperative outcomes and quality of life using the EORTC QLQ-C30 questionnaire.

Potential Biases

The study may be subject to bias due to the self-reported nature of quality of life assessments.

Limitations

The study is retrospective and may have bias due to the questionnaire return rate.

Participant Demographics

The study population consisted of 146 patients, predominantly female (74.7%), with a median age of 44 years.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1471-2482-11-16

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication