Elevated serum triglycerides is the strongest single indicator for the presence of metabolic syndrome in patients with type 2 diabetes
2006

Serum Triglycerides as a Predictor of Metabolic Syndrome in Type 2 Diabetes

Sample size: 500 publication Evidence: moderate

Author Information

Author(s): Kompoti Maria, Mariolis Anargiros, Alevizos Alevizos, Kyrazis Ioannis, Protopsaltis Ioannis, Dimou Eleni, Lentzas Ioannis, Levisianou Dimitrios, Gova Afroditi, Melidonis Andreas

Primary Institution: Department of General Practice/Family Medicine, Health Centre of Vyronas, Athens, Greece

Hypothesis

Can a single clinical parameter effectively predict the presence of metabolic syndrome in patients with type 2 diabetes?

Conclusion

Elevated serum triglycerides strongly indicate the presence of metabolic syndrome in patients with type 2 diabetes.

Supporting Evidence

  • 364 out of 500 patients were diagnosed with metabolic syndrome according to NCEP ATP III criteria.
  • 408 out of 500 patients were diagnosed with metabolic syndrome according to IDF criteria.
  • Serum triglycerides had the highest predictive capability for metabolic syndrome in the overall population.
  • In females, HDL and waist circumference also showed high predictive capability for metabolic syndrome.
  • Statistical analysis indicated significant differences in predictive capabilities between genders.

Takeaway

If you have diabetes and high triglycerides, you might also have a condition called metabolic syndrome, which can lead to heart problems.

Methodology

Patients with type 2 diabetes were studied over three months, measuring waist circumference, blood pressure, and serum lipids to diagnose metabolic syndrome.

Limitations

The sample size was not large enough to detect small differences, and the population was selected from an outpatient clinic.

Participant Demographics

231 males and 269 females with type 2 diabetes.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% confidence intervals (CI) 0.685–0.939

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1475-2840-5-21

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