Prostasome-like vesicles stimulate acrosome reaction of pig spermatozoa
2008
Prostasome-like vesicles stimulate acrosome reaction of pig spermatozoa
Sample size: 16
publication
Evidence: moderate
Author Information
Author(s): Laura Siciliano, Vito Marcianò, Amalia Carpino
Primary Institution: Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy
Hypothesis
Do prostasome-like vesicles in pig semen interact with spermatozoa and affect the acrosome reaction?
Conclusion
Pig prostasome-like vesicles can interact with spermatozoa and stimulate the acrosome reaction.
Supporting Evidence
- Prostasome-like vesicles were isolated from pig seminal plasma.
- Significant increase in acrosome reaction was observed in spermatozoa incubated with vesicles.
- Vesicles transferred aminopeptidase activity to sperm cells.
Takeaway
This study found that tiny particles in pig semen can help sperm get ready to fertilize an egg.
Methodology
Prostasome-like vesicles were isolated from pig semen and their interaction with spermatozoa was tested using various assays.
Participant Demographics
16 fertile male pigs, aged 20 to 30 months, weighing 300 to 360 kg.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website