The prognostic significance of facial lymphoedema in HIV-seropositive subjects with Kaposi sarcoma
2008

Facial Lymphoedema and Kaposi Sarcoma in HIV Patients

Sample size: 2 publication Evidence: low

Author Information

Author(s): Feller L, Masipa JN, Wood NH, Raubenheimer EJ, Lemmer J

Primary Institution: University of Limpopo School of Dentistry, Pretoria, South Africa

Hypothesis

The onset of facial lymphoedema in HIV-seropositive subjects with Kaposi sarcoma may indicate a poor prognosis.

Conclusion

Facial lymphoedema in HIV-seropositive patients with Kaposi sarcoma is associated with rapid disease progression and death.

Supporting Evidence

  • Facial lymphoedema is a prominent feature of HIV-associated Kaposi sarcoma.
  • The two reported cases showed rapid progression to death following the onset of facial lymphoedema.
  • Patients with extensive oral HIV-KS lesions have a higher mortality rate.

Takeaway

If someone with HIV and Kaposi sarcoma has swelling in their face, it might mean they are very sick and could die soon.

Methodology

Case report of two HIV-seropositive patients with Kaposi sarcoma and facial lymphoedema.

Potential Biases

Potential bias due to the small sample size and lack of control group.

Limitations

The study is based on only two case reports, limiting generalizability.

Participant Demographics

Two HIV-seropositive males, aged 28 and 55.

Digital Object Identifier (DOI)

10.1186/1742-6405-5-2

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication