Smoking-attributable peptic ulcer disease mortality worldwide: trends from 1990 to 2021 and projections to 2046 based on the global burden of disease study
2024

Trends in Smoking-Related Peptic Ulcer Disease Deaths

publication Evidence: high

Author Information

Author(s): Li Hao, Shi Qi, Chen Caiyun, Li Ju, Wang Kai

Primary Institution: The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University

Hypothesis

This study aims to analyze global trends in smoking-attributable PUD mortality from 1990 to 2021 and project future trends to 2046.

Conclusion

Global smoking-attributable PUD mortality has significantly decreased and is projected to continue declining, but substantial regional disparities persist.

Supporting Evidence

  • Global smoking-attributable PUD deaths decreased from 48,900 to 29,400 from 1990 to 2021.
  • The age-standardized mortality rate dropped from 1.2 to 0.3 per 100,000.
  • High-income regions showed faster declines in smoking-attributable PUD mortality.

Takeaway

Smoking makes people sick with stomach ulcers, but fewer people are dying from this now. However, some places still have a lot of problems with it.

Methodology

Data were obtained from the Global Burden of Disease Study 2021, calculating age-standardized mortality rates and using Bayesian Age-Period-Cohort models for projections.

Limitations

Data quality may be suboptimal for some countries, and the model may not fully capture future uncertainties or the impact of emerging tobacco products.

Statistical Information

P-Value

0.148

Statistical Significance

p=0.148

Digital Object Identifier (DOI)

10.3389/fpubh.2024.1465452

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