The treatment of primary and metastatic renal cell carcinoma (RCC) with image-guided stereotactic body radiation therapy (SBRT)
2007

Using Stereotactic Body Radiation Therapy for Kidney Cancer

Sample size: 16 publication Evidence: moderate

Author Information

Author(s): Teh BS, Bloch C, Galli-Guevara M, Doh L, Richardson S, Chiang S, Yeh P, Gonzalez M, Lunn W, Marco R, Jac J, Paulino AC, Lu HH, Butler EB, Amato RJ

Primary Institution: Department of Radiation Oncology, The Methodist Hospital, Houston, Texas, United States

Hypothesis

Can image-guided stereotactic body radiation therapy (SBRT) effectively treat primary and metastatic renal cell carcinoma (RCC)?

Conclusion

Image-guided SBRT provides excellent symptom relief and local control without significant toxicity.

Supporting Evidence

  • 93% of patients with extra-cranial metastases achieved significant pain relief.
  • Local control rate was 87% after treatment.
  • Patients reported improvement in quality of life and reduced need for pain medications.
  • There were no significant treatment-related side effects observed.

Takeaway

Doctors used a special type of radiation therapy to help patients with kidney cancer feel better and control their tumors without hurting them.

Methodology

Patients were treated with SBRT using the Brainlab Novalis system, with image guidance and various radiation doses over 3-6 fractions.

Limitations

The study had a small number of patients and short follow-up time.

Participant Demographics

Patients included 14 with metastatic RCC and 2 with primary RCC, all with various medical issues.

Digital Object Identifier (DOI)

10.2349/biij.3.1.e6

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