INTERLEUKIN-6 DRIVES MITOCHONDRIAL DYSREGULATION AND ACCELERATES PHYSICAL DECLINE: INSIGHTS FROM AN INDUCIBLE HUMANIZED IL-6 KNOCK-IN MOUSE MODEL
2024

Interleukin-6 and Physical Decline

publication

Author Information

Author(s): Abadir Peter

Primary Institution: Johns Hopkins University

Hypothesis

Interleukin-6 drives mitochondrial dysregulation and accelerates physical decline.

Conclusion

The study suggests that interleukin-6 may play a significant role in accelerating physical decline through its effects on mitochondrial function.

Takeaway

Interleukin-6 is a substance in the body that can make you weaker and less active as you get older.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0568

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