MULTIMORBIDITY PATTERNS PREDICT THE ORDER OF PHYSICAL FRAILTY AND COGNITIVE IMPAIRMENT OCCURRENCE
2024
Multimorbidity Patterns and Their Impact on Frailty and Cognitive Impairment
Sample size: 6055
publication
Evidence: moderate
Author Information
Author(s): Wang Shuomin, Li Qianyuan, Xue Qian-Li, Liu Minhui
Primary Institution: Central South University
Hypothesis
Do different multimorbidity patterns predict the order of frailty and cognitive impairment occurrence?
Conclusion
Multimorbidity patterns significantly influence the order in which frailty and cognitive impairment occur in older adults.
Supporting Evidence
- Four multimorbidity patterns were identified: cardiometabolic, osteoarticular, cancer-dominated, and multisystem.
- The multisystem pattern had a threefold higher risk of developing frailty first.
- Older adults in the cardiometabolic, osteoarticular, and cancer-dominated patterns had a decreased risk of cognitive impairment-first occurrence.
Takeaway
Older people with multiple health issues can get weak or have memory problems in different orders, depending on their specific health conditions.
Methodology
Latent class analysis and Fine & Gray competing risks models were used to analyze the data.
Participant Demographics
Community-dwelling older adults free of frailty or cognitive impairment at baseline.
Statistical Information
Confidence Interval
95% CI= 2.21-4.26
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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