Autistic Traits and Brain Activation during Face-to-Face Conversations in Typically Developed Adults
2011

Autistic Traits and Brain Activation during Face-to-Face Conversations

Sample size: 28 publication Evidence: moderate

Author Information

Author(s): Suda Masashi, Takei Yuichi, Aoyama Yoshiyuki, Sakurai Kosuke, Fukuda Noriko, Mikuni Masahiko

Primary Institution: Gunma University Graduate School of Medicine

Hypothesis

Face-to-face conversations would activate the PFC as well as the STS, and variations in autistic traits in typically developed participants would be correlated with brain activation during these conversations.

Conclusion

The study found that higher levels of autistic traits were associated with lesser brain activation in the left STS during face-to-face conversations.

Supporting Evidence

  • Both the PFC and STS were significantly activated during face-to-face conversations.
  • AQ scores were negatively correlated with regional cerebral blood volume increases in the left STS during conversations, especially in males.
  • NIRS allowed monitoring of brain function in a natural setting suitable for social interactions.

Takeaway

This study looked at how people's brains work when they talk to each other, especially focusing on those who might have traits of autism. It found that those with more autistic traits showed less brain activity in a certain area when having conversations.

Methodology

The study used near-infrared spectroscopy (NIRS) to monitor brain activation in 28 typically developed participants during face-to-face conversations.

Potential Biases

The study may have selection bias as it included only medical interns and students.

Limitations

The sample size was small and consisted only of medical students, which may not represent the general population.

Participant Demographics

28 healthy volunteers (14 males and 14 females; average age 26.4 years).

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0020021

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication