Survival Factors in Oesophageal Cancer Patients Undergoing Radiotherapy
Author Information
Author(s): Hajian-Tilaki K O
Primary Institution: Babol University of Medical Sciences
Hypothesis
What factors affect the survival of patients with oesophageal carcinoma under radiotherapy?
Conclusion
Patients with oesophageal cancer have a poor prognosis, with survival rates significantly influenced by age, gender, and radiotherapy dosage.
Supporting Evidence
- Survival rates were 42% at 1 year, 21% at 2 years, and 8% at 5 years after diagnosis.
- Patients aged 50–64 had poorer survival compared to those under 50.
- Females had significantly better survival than males.
- Each 100 rads dose of radiotherapy decreased the risk ratio by 1%.
- Each session of radiotherapy decreased the risk ratio by 4%.
- Surface area under radiotherapy increased the risk ratio.
Takeaway
This study looked at how different things affect how long people with oesophageal cancer live after getting radiation treatment. It found that older people and men tend to live shorter lives after treatment.
Methodology
An analytical study using a historical cohort and medical charts of patients with oesophageal cancer, analyzed using survival analysis methods.
Limitations
The study only included patients with available addresses and did not observe significant differences based on histology or treatment type.
Participant Demographics
Patients referred to the Shahid Rajaii radiotherapy centre in Babolsar, with a focus on those aged 50 and older.
Statistical Information
P-Value
P = 0.03
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website