Antioxidant, Anti-Inflammatory, and Anticancer Activities of Five Citrus Peel Essential Oils
2024

Antioxidant, Anti-Inflammatory, and Anticancer Activities of Five Citrus Peel Essential Oils

publication Evidence: high

Author Information

Author(s): Li Yurong, Li Wenji, Ye Zimao, Ji Chen, Zhou Zhiqin, Napolitano Alessandra

Primary Institution: Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River, Ministry of Education, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China

Hypothesis

This study aimed to explore the health-promoting and anticancer effects of citrus peel essential oils (CPEOs) from different cultivated varieties.

Conclusion

Citrus peel essential oils possess excellent antioxidant, anti-inflammatory, and anticancer activity potential, making them suitable for use in functional foods and nutritional health products.

Supporting Evidence

  • Citrus peel essential oils can increase antioxidant enzyme activity and reduce oxidative stress in cells.
  • Citrus peel essential oils reduce inflammation by decreasing nitric oxide production and proinflammatory cytokine expression.
  • Citrus peel essential oils induce apoptosis in glioblastoma cells through the mitochondrial apoptotic pathway.
  • All five types of citrus peel essential oils exhibited good antioxidant and anti-inflammatory activities.

Takeaway

Citrus peel oils can help protect our bodies from damage and may even fight cancer, making them good for our health.

Methodology

The study evaluated the antioxidant, anti-inflammatory, and anticancer activities of CPEOs through cell experiments, including viability assays, oxidative stress models, and apoptosis analysis.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/antiox13121562

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