Inquilinus limosus and Cystic Fibrosis
Author Information
Author(s): Bittar Fadi, Leydier Anne, Bosdure Emmanuelle, Toro Alexandre, Reynaud-Gaubert Martine, Boniface Stéphanie, Stremler Nathalie, Dubus Jean-Christophe, Sarles Jacques, Raoult Didier, Rolain Jean-Marc
Primary Institution: Université de la Méditerranée, Marseille, France
Hypothesis
This bacterium is selected during the evolution of the disease.
Conclusion
The study developed a real-time PCR method that can detect Inquilinus limosus in cystic fibrosis patients more effectively than traditional culture methods.
Supporting Evidence
- 9 I. limosus-positive samples were detected from 4 patients with cystic fibrosis.
- 8 of these samples were also culture positive.
- All sputum samples from patients without cystic fibrosis were negative.
- The incidence of I. limosus was 2.8% among patients with cystic fibrosis.
Takeaway
Researchers found a new way to quickly detect a harmful bacteria in cystic fibrosis patients, which can help doctors treat infections sooner.
Methodology
A real-time PCR assay was developed and compared with culture isolation to detect I. limosus in sputum samples.
Limitations
The study may not account for all potential cases of I. limosus due to the limitations of culture methods.
Participant Demographics
The study included 84 children and 61 adults with cystic fibrosis.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website