Molecular Epidemiology of Foot-and-Mouth Disease Virus in Turkey
Author Information
Author(s): Klein Joern, Parlak Ünal, Özyörük Fuat, Christensen Laurids S
Primary Institution: Danish Institute for Food and Veterinary Research
Hypothesis
What is the genetic diversity of Foot-and-Mouth Disease virus serotypes A and O in Turkey from 1998 to 2004?
Conclusion
The study found that the IRN99 strain of Foot-and-Mouth Disease virus likely originated from Iran and suggests that outbreaks in 2004 were due to incomplete vaccine coverage.
Supporting Evidence
- The study confirmed the presence of two major serotype A lineages, IRN99 and IRN96, in Turkey.
- Evidence of positive selection was found in the IRN99 strain, suggesting an immunological advantage.
- Outbreaks caused by IRN96 strains in 2004 could be due to incomplete vaccine coverage.
Takeaway
Scientists studied the Foot-and-Mouth Disease virus in Turkey to see how it changed over time, and they found that one type of the virus probably came from Iran.
Methodology
The study sequenced the 1D coding region of 33 serotype O and 20 serotype A isolates collected from outbreaks between 1998 and 2004.
Limitations
The small sample size may limit the conclusions about the presence of the A22 strain in Turkey.
Participant Demographics
Isolates were collected from bovine herds widely distributed in Turkey.
Statistical Information
P-Value
p = 0.29
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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