Obesity and Accelerated Aging
2024

Obesity and Accelerated Aging

publication

Author Information

Author(s): Dennis Villareal

Primary Institution: Baylor College of Medicine

Hypothesis

Obesity contributes to accelerated aging through various biological mechanisms.

Conclusion

Obesity is linked to accelerated aging due to chronic inflammation, oxidative stress, and DNA damage.

Supporting Evidence

  • Obesity is associated with a decline in physical function and quality of life.
  • Chronic low-grade inflammation is a common feature of both obesity and aging.
  • Obesity can lead to oxidative stress, which damages cellular structures.
  • DNA damage from obesity may accelerate aging processes.

Takeaway

Being overweight can make you age faster because it causes problems in your body that are similar to getting older.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0323

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