The benefits of contrast-enhanced ultrasound in the differential diagnosis of suspicious breast lesions
2024

Using Contrast-Enhanced Ultrasound to Diagnose Suspicious Breast Lesions

Sample size: 150 publication Evidence: high

Author Information

Author(s): Liang Runa, Lian Jun, Zhang Jinhui, Jing Jiayu, Bian Jinxia, Xu Jinzhi, He Xin, Yu Shanshan, Zhou Qi, Jiang Jue

Primary Institution: The Second Affiliated Hospital of Xi’an Jiaotong University

Hypothesis

This study aimed to evaluate the diagnostic value of CEUS in differentiating pathological subtypes of suspicious breast lesions defined as category 4 of US-BI-RADS.

Conclusion

Some qualitative risk features of CEUS can distinguish malignant breast lesions from NPMs and atypical FIBs with high US-BI-RADS scores, aiding physicians to reduce the misdiagnosis of suspicious breast lesions in clinical practice.

Supporting Evidence

  • Qualitative features like crab clam-like enhancement can help differentiate between benign and malignant lesions.
  • IMAX was the only quantitative parameter that significantly contributed to the differential diagnosis.
  • The integrated model showed high diagnostic efficiency with an AUCROC of 0.89.

Takeaway

Doctors can use special ultrasound techniques to tell the difference between bad and not-so-bad lumps in women's breasts, which helps them avoid making mistakes.

Methodology

The study analyzed 150 breast lesions from patients who underwent routine ultrasound and CEUS, with all lesions confirmed by biopsy and surgery.

Limitations

The study had limitations in differentiating between certain histopathological subtypes of breast lesions.

Participant Demographics

The average age of patients with malignant lesions was 52.8 years, and with benign lesions was 44.6 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

(0.52: 0.72)

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fmed.2024.1511200

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