Endoscopic Bulking Materials for the Treatment of Vesicoureteral Reflux: A Review of Our 20 Years of Experience and Review of the Literature
2011

Endoscopic Bulking Materials for Vesicoureteral Reflux Treatment

Sample size: 507 publication Evidence: low

Author Information

Author(s): Chertin Boris, Kocherov Stanislav, Chertin Leonid, Natsheh Alaeddin, Farkas Amicur, Shenfeld Ofer Z., Halachmi Sarel

Primary Institution: Shaare Zedek Medical Center, Faculty of Medical Science, Hebrew University

Hypothesis

What are the long-term outcomes of endoscopic treatment of vesicoureteral reflux using different bulking agents?

Conclusion

There is a high recurrence rate during long-term follow-up after dextranomer hyaluronic acid injection, indicating a need for close observation and further studies.

Supporting Evidence

  • Short-term success rates of endoscopic treatment range from 68% to 92% depending on the reflux grade.
  • High recurrence rates were noted, especially with dextranomer hyaluronic acid injections.
  • Only 2.2% of children developed febrile urinary tract infections after successful endoscopic correction.

Takeaway

Doctors have been using special materials to help kids with a problem called vesicoureteral reflux, but many kids still have issues later on, so they need to be watched closely.

Methodology

The study reviewed 20 years of experience and literature on endoscopic treatment outcomes for vesicoureteral reflux using various bulking agents.

Limitations

There is a significant shortage of evidence-based literature on long-term follow-up after endoscopic correction of reflux.

Participant Demographics

The study included 507 patients, 169 males and 338 females, with a median age of 3.7 years.

Digital Object Identifier (DOI)

10.1155/2011/309626

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