Inulin's Effect on Milk MicroRNAs in Dairy Cows with Mastitis
Author Information
Author(s): Wanjie Yu, Xuemei Nan, Martine Schroyen, Yue Wang, Mengting Zhou, Xiangfang Tang, Benhai Xiong
Primary Institution: University of Liège, Gembloux Agro-Bio Tech
Hypothesis
Supplementing inulin in the diet could alter bovine milk-derived sEVs-miRNA profiles.
Conclusion
Inulin supplementation impacts the expression of bovine milk sEVs-miRNA and alters the highly expressed miRNA in cows with subclinical mastitis.
Supporting Evidence
- 350 miRNAs were discovered, with 9 showing differential expression between the inulin and control groups.
- DE miRNAs participate in regulating organismal systems, cellular processes, and signal transduction.
- Inulin supplementation may help mitigate subclinical mastitis by regulating microbial communities and metabolites.
Takeaway
Giving cows inulin can change the tiny molecules in their milk that help control inflammation and improve milk production.
Methodology
Fourteen lactating cows with subclinical mastitis were divided into inulin and control groups, receiving either 300 g/d inulin or no supplement for 5 weeks, followed by analysis of milk-derived sEVs-miRNA.
Potential Biases
Potential individual differences among cows may affect the results.
Limitations
The study was limited to a specific dose of inulin and a small sample size.
Participant Demographics
Fourteen Holstein dairy cows diagnosed with subclinical mastitis.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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