Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines
2007

Study of Gene Expression in Soybean Cyst Nematode

Sample size: 21000 publication 10 minutes Evidence: high

Author Information

Author(s): Elling Axel A, Mitreva Makedonka, Recknor Justin, Gai Xiaowu, Martin John, Maier Thomas R, McDermott Jeffrey P, Hewezi Tarek, McK Bird David, Davis Eric L, Hussey Richard S, Nettleton Dan, McCarter James P, Baum Thomas J

Primary Institution: Iowa State University

Hypothesis

Are the gene expression profiles of the dauer stage in Caenorhabditis elegans and the infective stage in Heterodera glycines conserved?

Conclusion

The study found that gene expression patterns and metabolic features are not shared between the developmentally arrested life stages of C. elegans and H. glycines, indicating divergent evolution.

Supporting Evidence

  • The study generated 20,100 expressed sequence tags (ESTs) for H. glycines.
  • A total of 6,860 unique genes were identified and profiled.
  • Gene expression patterns were analyzed across multiple life stages of H. glycines.

Takeaway

This study looked at how two types of tiny worms, one that lives in the soil and one that infects plants, grow and change. It found that they do it in very different ways.

Methodology

The study involved generating and analyzing over 20,000 expressed sequence tags (ESTs) to identify and profile gene expression in H. glycines.

Limitations

The study did not include adult male stages of H. glycines in the analysis.

Statistical Information

P-Value

0.000015

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/gb-2007-8-10-r211

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