Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chloro­phen­yl)meth­yl]-3-methyl-6-oxopyridazin-1-yl}-N-phenyl­acetamide
2024

Study of a New Chemical Compound's Structure

publication Evidence: moderate

Author Information

Author(s): Assila Hamza, Zaoui Younes, Kalonji Mubengayi Camille, Guerrab Walid, Alsubari Abdulsalam, Mague Joel T., Ramli Youssef, Ansar Mhammed

Primary Institution: Laboratory of Medicinal Chemistry Drug Sciences Research Center Faculty of Medicine and Pharmacy Mohammed V University in Rabat Rabat Morocco

Hypothesis

The study aims to synthesize and analyze the crystal structure of a new pyridazine derivative.

Conclusion

The synthesized compound exhibits a unique crystal structure characterized by specific hydrogen bonding interactions.

Supporting Evidence

  • The compound's crystal structure was analyzed using Hirshfeld surface analysis.
  • The study found significant hydrogen bonding interactions in the crystal.
  • The phenyl-acetamide moiety was nearly planar due to specific hydrogen bonds.
  • The research contributes to the understanding of pyridazine derivatives.

Takeaway

Scientists made a new chemical and looked at how its tiny parts fit together. They found that it has some interesting connections that help hold it together.

Methodology

The compound was synthesized through a reflux reaction and characterized using various analytical techniques including Hirshfeld surface analysis.

Digital Object Identifier (DOI)

10.1107/S2056989024010296

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