Dengue haemorrhagic fever among adults – An observational study in Chennai, south India
2010

Dengue Hemorrhagic Fever in Adults: A Study in Chennai

Sample size: 128 publication Evidence: moderate

Author Information

Author(s): Bhaskar M. Emmanuel, Moorthy Swathy Kumar N., Senthil Arthur Preetam

Primary Institution: Sri Ramachandra Medical College & Research Institute

Hypothesis

The study aims to observe the clinical presentation and factors associated with mortality due to dengue hemorrhagic fever among adults in Chennai.

Conclusion

Dengue hemorrhagic fever is spreading across all age groups in Chennai, and the mortality rate observed was 14%.

Supporting Evidence

  • 14% of the patients died during the study.
  • Patients with renal failure and refractory shock had a higher mortality risk.
  • Symptoms included fever, myalgia, and bleeding tendencies.

Takeaway

Dengue can make people very sick, and in this study, many adults got really sick and some even died from it.

Methodology

The study included adult patients admitted with dengue hemorrhagic fever, following WHO case definitions, and involved clinical assessments and laboratory tests.

Potential Biases

There may be bias due to the focus on severe cases, potentially overlooking milder cases.

Limitations

The study may have selection bias as it only included patients with severe illness.

Participant Demographics

Patients were adults aged over 18, with a mean age of 33 years, and an equal proportion of males and females.

Statistical Information

P-Value

P<0.001 for several factors associated with mortality.

Statistical Significance

p<0.05

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication