Regional Variations in the Incidence of Lichen Sclerosus in Sweden: Insights from a Nationwide Register Study (2001–2021)
2024

Regional Variations in Lichen Sclerosus Incidence in Sweden

Sample size: 154424 publication 10 minutes Evidence: high

Author Information

Author(s): Sandra Jerkovic Gulin, Georgios Kravvas, Oliver Seifert

Primary Institution: Department of Dermatology and Venereology, Ryhov County Hospital, Sweden

Hypothesis

This study aims to examine the incidence, demographic characteristics, and regional distribution of Lichen Sclerosus in Sweden over a 20-year period.

Conclusion

The study highlights significant regional variations in the incidence of Lichen Sclerosus across Sweden.

Supporting Evidence

  • The mean annual incidence of LSc was 0.81 per 1000 individuals across Sweden.
  • Females had a higher incidence rate of 1.14 per 1000 compared to males at 0.47 per 1000.
  • Regions like Blekinge, Kalmar, and Gotland exhibited the highest incidence rates.

Takeaway

Lichen Sclerosus is a skin condition that affects people in different parts of Sweden at different rates, especially more in women than men.

Methodology

A nationwide register-based study using data from the Swedish National Patient Register to identify cases of LSc diagnosed between 2001 and 2021.

Potential Biases

Potential underreporting of LSc cases diagnosed in primary care settings.

Limitations

The study does not include primary care data, which may lead to an underestimation of the true incidence of LSc.

Participant Demographics

The study included 154,424 individuals diagnosed with LSc, with a focus on demographic characteristics such as sex and age.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 29.2–30.1%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/jcm13247836

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