Risk Factors for Gangrenous Cholecystitis in Eastern India
Author Information
Author(s): Muacevic Alexander, Adler John R, V Karthikarajam, Pushpaketu Nalubolu, Badhai Samit, Mishra Amaresh, Sahu Subrat, Debata Ipsita, Debata P. K.
Primary Institution: Kalinga Institute of Medical Sciences, Bhubaneswar, IND
Hypothesis
What are the factors that can predict gangrenous changes in patients with acute cholecystitis?
Conclusion
The study identified several demographic, clinical, and imaging factors that are linked to a high risk of developing gangrenous cholecystitis.
Supporting Evidence
- 27 out of 340 patients with acute cholecystitis progressed to gangrenous cholecystitis.
- 81.5% of gangrenous cholecystitis cases were male.
- 55.5% of gangrenous cholecystitis cases were in the 51-70 years age group.
- 85.2% of gangrenous cholecystitis cases had comorbidities.
- Fever and vomiting were significantly associated with gangrenous outcomes.
Takeaway
This study looked at what makes some people with gallbladder problems more likely to get really sick. It found that older men and those with other health issues are at higher risk.
Methodology
A prospective cohort study was conducted among 340 patients diagnosed with acute cholecystitis, analyzing data through descriptive statistics and various statistical tests.
Potential Biases
The study aimed to minimize selection bias by including all eligible patients meeting the criteria.
Limitations
The study did not explore the association between clinical signs and symptoms with the outcome of acute cholecystitis in detail.
Participant Demographics
The study included 58.8% females and 41.2% males, with a significant portion aged between 31 and 70 years.
Statistical Information
P-Value
p < 0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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