Histiocytic Lymphoma of Breast Responds to Tamoxifen
Author Information
Author(s): R.R. Millis, L.G. Bobrow, R.D. Rubens, P.G. Isaacson
Primary Institution: Imperial Cancer Research Fund, Clinical Oncology Unit, Guy's Hospital
Hypothesis
Can tamoxifen be effective in treating primary malignant lymphoma of the breast?
Conclusion
The patient showed a long-term, complete remission after being treated with tamoxifen for histiocytic lymphoma of the breast.
Supporting Evidence
- The patient was initially misdiagnosed with anaplastic mammary carcinoma.
- Tamoxifen treatment led to a decrease in size of pulmonary metastases within two weeks.
- Complete resolution of pulmonary secondaries was maintained for 47 months.
Takeaway
A woman with a rare type of breast cancer responded well to a medication usually used for other types of cancer.
Methodology
The patient was treated with tamoxifen and monitored for response through radiological assessments.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
The patient was a 50-year-old woman with a history of breast pain and swelling.
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