Hip Fracture Risk in Older Diabetic Adults
Author Information
Author(s): E. S. Strotmeyer, A. Kamineni, J. A. Cauley, J. A. Robbins, L. F. Fried, D. S. Siscovick, T. B. Harris, A. B. Newman
Primary Institution: University of Pittsburgh
Hypothesis
Are type 2 diabetes and impaired fasting glucose independently associated with a higher risk for hip fractures in older adults?
Conclusion
Diabetes is associated with a higher risk of hip fractures in older adults, particularly when adjusted for body mass index.
Supporting Evidence
- Diabetes was related to fractures with a hazard ratio of 1.34 after adjusting for BMI.
- Crude hip fracture rates were higher for diabetic participants compared to non-diabetic participants.
- Subclinical peripheral artery disease modified the fracture risk in diabetes.
Takeaway
Older adults with diabetes are more likely to break their hips, even if they weigh the same as non-diabetics.
Methodology
The study followed 5641 participants over approximately 10.9 years, assessing diabetes status and incident hip fractures through medical records.
Potential Biases
Participants with more severe diabetes may have been less likely to participate, potentially underestimating fracture risk.
Limitations
The study did not measure bone mineral density or diabetes duration, which may affect fracture risk.
Participant Demographics
Participants were predominantly older adults (mean age 72.8 years), with 42% men and 15.5% black.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI: 1.01–1.78
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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