Echocardiographic predictors of early in-hospital heart failure during first ST-elevation acute myocardial infarction: does myocardial performance index and left atrial volume improve diagnosis over conventional parameters of left ventricular function?
2011

Echocardiographic Predictors of Heart Failure in Myocardial Infarction

Sample size: 95 publication Evidence: high

Author Information

Author(s): Lilian P Souza, Orlando Campos, Clovis A Peres, Cristiano V Machado, Antonio C Carvalho

Primary Institution: Escola Paulista de Medicina, Federal University of Sao Paulo, UNIFESP, Brazil

Hypothesis

Can myocardial performance index and left atrial volume improve diagnosis of early heart failure over conventional parameters of left ventricular function?

Conclusion

Left ventricular ejection fraction is a strong predictor of early heart failure in patients with first ST-elevation myocardial infarction.

Supporting Evidence

  • 31% of patients developed early in-hospital CHF.
  • LVEF ≤ 0.45 was the single independent predictor of early CHF.
  • MPI alone could not predict CHF in first ST-elevation AMI patients.

Takeaway

Doctors can tell if a heart is in trouble after a heart attack by looking at how well it pumps blood, especially if it pumps less than half of the blood it should.

Methodology

Echocardiography was performed within 30 hours of chest pain in 95 patients with first ST-elevation AMI, and multivariate regression analysis was used to identify predictors of in-hospital CHF.

Limitations

The study did not include E/e' velocities ratio, which could be a valuable prognostic index.

Participant Demographics

Mean age 58 years, 64 males.

Statistical Information

P-Value

p<0.0001

Confidence Interval

[95% CI 4.1 - 70.8]

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1476-7120-9-17

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